New crystal material powers Siemens camera

AuntMinnie.com staff writers

Jun 6, 2000

A new type of scintillation crystal made from lutetium oxyortho-silicate (LSO) is at the heart of a new PET imager unveiled at this week's Society of Nuclear Medicine meeting by Siemens Medical Systems and its PET development partner, CTI of Knoxville, TN. The companies hope the material will enable users of the new camera, LSO ECAT Accel, to cut PET scanning times in half, from 40 minutes to 20.

Siemens and CTI have been investigating the use of LSO as an alternative to the sodium iodide (NaI) crystals used in gamma cameras and the bismuth germanate (BGO) crystals found in PET systems. The companies believe LSO can provide good high-energy imaging characteristics at a lower price than BGO-based PET cameras.

LSO ECAT Accel is being shown as a work-in-progress at the SNM show, according to the companies. The camera will operate on computer hardware and software similar to other cameras in the Siemens PET family.

By AuntMinnie.com staff writers
June 7, 2000

Copyright © 2000 AuntMinnie.com

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PET/CT images of F-18 AlF-NOTA-BCP137 in patients with hepatocellular carcinoma (HCC) and immunofluorescence analysis of patient tissues. (A) F-18 AlF-NOTA-BCP137 PET/CT images before and after immunotherapy for patient 1 and patient 2. (B) F-18 AlF-NOTA-BCP137 PET/CT and MR images of patient 3 (left panels) after one cycle of immunotherapy. PET images showed higher uptake by tumor and spleen, and PET result was evaluated as positive; therefore, the patient was considered to be responder to treatment and underwent surgical resection. Representative images of hematoxylin and eosin (HE) staining and multiplex immunofluorescence of CD8 and CD137 (right panels) in HCC tumor and adjacent normal tissues of patient 3 after surgery. Nuclei were stained with 4′,6-diamidino-2-phenylindole. Primary tumors are indicated by white arrows, and increased thyroid uptake is indicated by red arrow in PET images. Image courtesy of the Journal of Nuclear Medicine.

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