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Molecular Imaging

ARRS: MBI has considerations for streamlining breast imaging workflows
By Amerigo Allegretto
An ARRS presentation addressed how MBI workflows can be streamlined.
April 13, 2026
Screenshot (127)
New PET tracer shows promise in dementia
By Will Morton
SV2A PET may offer a robust, sensitive biomarker for disease staging, treatment monitoring.
April 10, 2026
(A) Averaged parametric images of F-18 SynVesT-1 BPND values and (B) F-18 FDG SUVR (60–90 minutes) values overlaid on anatomical (T1) images in MNI space show group differences between behavioral variant frontotemporal dementia (top) and healthy controls (middle). The color scale represents (A) BPND and (B) SUVR values. On the bottom, average z-score maps were generated to visualize regional reductions in F-18 SynVesT-1 BPND and F-18 FDG SUVR in bvFTD relative to healthy controls. For each voxel, z-scores were calculated as z = (bvFTD−meanHC )/SDHC. Negative z-scores indicate lower synaptic density or glucose metabolism in the bvFTD compared with controls in the regions. BPND, non-displaceable binding potential; bvFTD, behavioral variant frontotemporal dementia; F-18 FDG, F-18 fluorodeoxyglucose; MNI, Montreal Neurological Institute; SUVR, standardized uptake value ratio.
FDA accepts Telix NDA for glioma PET agent Pixclara
By AuntMinnie.com staff writers
The NDA resubmission included additional data and statistical analysis requested by the U.S. FDA.
April 10, 2026
Pet Brain Scan Adobe Michael dim5r Awl G7
PET links brain metabolism to survival in lung cancer patients
By Will Morton
Low brain metabolic activity was associated with increased mortality in patients with advanced NSCLC.
April 9, 2026
A visual abstract of the study
Shine receives $263M conditional loan for Mo-99 isotope facility
By AuntMinnie.com staff writers
Shine has received a conditional loan from the U.S. DOE to complete the Chrysalis medical isotope production facility for Mo-99.
April 9, 2026
Chrysalis, Shine’s large-scale irradiation facility, will complement the existing supply chain with the goal of ensuring a sustainable and reliable source of isotopes, including Mo-99.
First patients treated in RYZ401 radiopharmaceutical trial
By AuntMinnie.com staff writers
RYZ401 is an investigational actinium-225 (AC-225)-based radiopharmaceutical targeting somatostatin receptors in neuroendocrine tumors.
April 8, 2026
Atom Molecule
New method decouples Alzheimer's disease pathology at PET
By Liz Carey
AI-derived scoring tool shows independent associations, according to researchers.
April 7, 2026
Adversarial decomposition learning (ADL) enables intuitive, longitudinal visualization of disease progression and treatment response, supporting clinician–artificial intelligence collaboration. (A) Images in a 48-year-old female patient who presented with mild cognitive impairment. The ADL probability maps highlighted occipital-temporal amyloid β (Aβ) spread and focal left-temporal tau pathologic abnormalities. An area of increased occipital AV45 uptake is shown (arrowhead). (B) Images in a 51-year-old male who presented with memory decline. For each image grid, the left side is the decoupler-output AD pathologic probability map, the upper right side is the original Aβ/tau PET image, and the lower right side is the image after AD component removal by the decoupler.
Consortium launches 5-year plan to improve theranostics outcomes
By Will Morton
The project aims to pave the way for personalized radiopharmaceutical therapy.
April 6, 2026
Isotopes1
SpectronRx raises $85M to expand radiopharmaceutical production
By AuntMinnie.com staff writers
The funding will support infrastructure investment at the company's Grissom Aeroplex campus in Indiana.
April 2, 2026
Cash
Catalyst MedTech expands brain PET deployment program
By AuntMinnie.com staff writers
The program integrates the CareMiBrain dedicated brain PET system with quantification tools, clinical workflow support, and service and maintenance.
April 1, 2026
Brain Pet
Cardinal Health expands Ac-225 production
By AuntMinnie.com staff writers
Since launching routine Ac-225 production at scale in late 2024, the company said it has quadrupled its weekly output.
April 1, 2026
Isotopes1
PET/CT metric improves outcome predictions in Pluvicto patients
By Will Morton
The inclusion of total tumor volume (TTV) produces prediction models with better discriminatory ability.
March 31, 2026
PSMA-PET images. (A) Representative examples illustrate the variability in the total tumor volume (TTV) among patients stratified by the number of metastatic lesions. (B) Case examples demonstrate TTV segmentation across a range of TTV values. Notably, as the tumor volume increased, a visible decrease in radiopharmaceutical uptake by normal organs is observed, particularly in the salivary glands, kidneys, and liver (denoted by brackets), a phenomenon known as the “sink effect.” SUV = standardized uptake value.
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