Positron emission mammography (PEM) developer Naviscan of San Diego is touting the results of a multiyear study of 388 women that found that PEM scanners significantly out-performed MRI to differentiate between benign and cancerous lesions.
The purpose of the U.S. National Institutes of Health (NIH)-funded study was to discover additional or secondary breast tumors to help direct treatment options. Researchers found that PEM scans accurately distinguished 151 of 180 benign additional lesions, for 80% specificity. Breast MRI had a specificity of 66%.
In addition, the study revealed that to increase reliability in identification of lesions, both technologies should be employed. PEM plus MRI scanning saw an additional 31 (out of 116 total) lesions, yielding a 20% absolute increase in sensitivity when compared with MRI alone.
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