Letter Services Article: Ultrasound Digital Community Redesign

May 11, 2010

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Burden of PSMA-expressing prostate cancer before and after treatment with two cycles of Lu-177 PSMA-617. (A and B) Reduction in overall disease burden is evident after treatment. Avidity of patient’s primary prostate tumor and his osseous metastasis shown before (C) and after (D) treatment.
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Case report: Pluvicto as a first-line treatment in late-stage prostate cancer
Since 1996, the patient continually declined androgen deprivation therapy, chemotherapy, and local therapy to the prostate gland.
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Burden of PSMA-expressing prostate cancer before and after treatment with two cycles of Lu-177 PSMA-617. (A and B) Reduction in overall disease burden is evident after treatment. Avidity of patient’s primary prostate tumor and his osseous metastasis shown before (C) and after (D) treatment.
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Study results point toward program directors focusing on administrative responsibilities rather than scholarly activity.
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3D DEXA may be a practical and valuable tool for detecting structural bone changes in prostate cancer patients.
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Adding MBI to DBT finds more breast cancers
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Adding molecular breast imaging (MBI) to DBT screening leads to more invasive cancers detected in women with dense breasts.
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Images in a 62-year-old woman who presented for screening. (A) Image from DBT screening (the synthesized 2D mediolateral oblique view of the left breast is shown) at year on was interpreted as negative and showing heterogeneously dense breast. (B) Image from molecular breast imaging screening (mediolateral oblique view) at year one reveals a 0.9-cm non-mass focal area of uptake in the left breast (arrow). (C) Targeted ultrasound scan (transverse image) shows a suspicious mass in the 3-o’clock position of the left breast, 4 cm from the nipple. Ultrasound-guided core biopsy and lumpectomy revealed a 0.9-cm grade 2 invasive ductal carcinoma, an estrogen receptor–negative, progesterone receptor–negative, human epidermal growth factor receptor 2–negative lesion, with two sentinel nodes negative (N0).
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