Dr. Anton Becker, PhD, and David Gugelmann, PhD

AI
AI-cyberterrorism in radiology: Threat or red herring?
In this Second Opinion article, Dr. Anton Becker, PhD, of Memorial Sloan Cancer Kettering Cancer in New York City and David Gugelmann, PhD, of Exeon Analytics assess the threat posed by artificial intelligence-powered cyberterrorism in radiology.
December 11, 2019
2019 03 26 18 32 2300 Computer Hacker Security 400
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Mammo uptake among veterans on par with nonveterans
Female veterans are as likely to undergo screening mammography as nonveteran women.
Patient examples of SPECT/CT and PET/CT RECIP 1.0. (A) SPECT and PET maximum-intensity projection (MIP) images in 74-year-old man with mCRPC. Serum PSA level at baseline was 449 ng/mL and slightly increased to 525 ng/mL after two cycles of Lu-177 PSMA. Eastern Cooperative Oncology Group (ECOG) score was 2 at baseline and increased to 3 after 2 cycles. The patient was classified by readers as RECIP-progressive disease on both SPECT and PET. Overall survival was 4.7 months. Two cycles of Lu-177 PSMA were administered. (B) SPECT and PET MIP images in 74-year-old man with mCRPC. Serum PSA level was 231 ng/mL at baseline and decreased to 12.5 ng/mL after 2 cycles of Lu-177 PSMA. ECOG score was less than 2 at baseline and after 2 cycles of Lu-177 PSMA. The patient was classified by readers as RECIP-partial response on both SPECT and PET. Overall survival was 14.3 months. Four cycles of Lu-177 PSMA were administered.
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SPECT/CT predicts overall survival in Pluvicto patients
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AI-assisted brain MRI shows promise for improved glioma care
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Patient examples of SPECT/CT and PET/CT RECIP 1.0. (A) SPECT and PET maximum-intensity projection (MIP) images in 74-year-old man with mCRPC. Serum PSA level at baseline was 449 ng/mL and slightly increased to 525 ng/mL after two cycles of Lu-177 PSMA. Eastern Cooperative Oncology Group (ECOG) score was 2 at baseline and increased to 3 after 2 cycles. The patient was classified by readers as RECIP-progressive disease on both SPECT and PET. Overall survival was 4.7 months. Two cycles of Lu-177 PSMA were administered. (B) SPECT and PET MIP images in 74-year-old man with mCRPC. Serum PSA level was 231 ng/mL at baseline and decreased to 12.5 ng/mL after 2 cycles of Lu-177 PSMA. ECOG score was less than 2 at baseline and after 2 cycles of Lu-177 PSMA. The patient was classified by readers as RECIP-partial response on both SPECT and PET. Overall survival was 14.3 months. Four cycles of Lu-177 PSMA were administered.
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Figure: Improved image quality with a generative adversarial network architecture for low- to high-field-strength image translation, called LowGAN. (A–C) Top: High-field-strength (3-T) and low-field-strength (64-mT) images and LowGAN outputs for a single participant across (A) fluid-attenuated inversion recovery (FLAIR), (B) T1-weighted (T1w), and (C) T2-weighted (T2w) contrasts. Bottom: Graphs demonstrate the structural similarity index (SSIM), peak signal-to-noise ratio (PSNR), normalized cross-correlation (NCC), and feature similarity index (FSIM) between high field strength and low field strength (64-mT) and high field strength and LowGAN outputs. a.u. = arbitrary units.****p ≤ 0.0001. Images and caption courtesy of Radiology and the RSNA.
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