Thursday, December 5 | 8:20 a.m.-8:30 a.m. | R1-SSNMMI07-3 | Room S405
A study in this session suggests that count-poor and noisy amyloid brain PET/CT studies can be rendered clinically useful through AI denoising software.
Researchers found that two-minute PET amyloid scans corrected by the software (SubtlePET, Subtle Medical) were indistinguishable from gold standard 10-minute amyloid PET scans.
Presenter Karin Knesaurek, PhD, of the Icahn School of Medicine at Mount Sinai in New York City, and colleagues, used a a time-of-flight PET/CT system (Biograph Vision 600 Edge, Siemens Healthineers) to acquire a patient amyloid brain PET/CT study in list mode, which allowed them to create the shorter reconstructed studies in addition to the 10-minute study. They compared the images visually as well as quantitatively by calculating standardized uptake value (SUV) ratios in six target cortical regions (anterior cingulate gyrus, inferior medial frontal gyrus, lateral temporal lobe, posterior cingulate gyrus, precuneus areas, and superior parietal lobule) along with the cerebellum.
In an image displaying the two-minute, 10-minute, and two-minute corrected amyloid PET scans, the visual similarity between the 10-minute and two-minute corrected scans was notable, according to the results. In addition, SUV ratio values in all six target areas were the same for both the 10-minute scan and the two-minute corrected scan.
“The results suggest that 2-minute corrected PET amyloid scans are virtually indistinguishable, both visually and quantitatively, from standard 10-minute PET amyloid scans,” the group concluded.
Stop by this scientific session on innovations in nuclear medicine to kick off your Thursday morning and learn all the details.
