Glucose loading in pregnant women affects color Doppler measurements

Sunday, December 1 | 3:00 p.m.-3:10 p.m. | S5-SSOB01-4 | Room E351

Here, attendees will learn about the effect of maternal glucose loading in pregnant women on color Doppler ultrasound parameters.

Gurudat Ramakant Shenoy, MBBS, from Shri Vinayaka Scan Centre Diagnostics and Polyclinic in Haveri, India, will present research demonstrating that increased maternal blood glucose levels after glucose loading results in lower fetal umbilical artery and middle cerebral artery pulsatility indices.

Shenoy and colleagues studied these effects on color Doppler parameters at zero hours and at two hours of glucose loading. The study included 5,600 singleton low-risk pregnancies with a gestational age of between 30 and 32 weeks.

In all cases, women were given an oral glucose tolerance test (OGTT) with 75 grams of glucose after 12 hours of fasting. The team correlated fetal heart rates at the corresponding times to Doppler findings of umbilical artery and middle cerebral artery pulsatility indices.

It found that the average maternal blood glucose levels at zero hours were significantly lower than after two hours of administering the OGTT (p = 0.002). Also, the umbilical artery pulsatility index decreased from zero hours to after two hours of OGTT (p = 0.041).

Fetal heart rate meanwhile significantly increased from zero hours to after two hours of the OGTT (p = 0.028).

Among other findings, the team showed that changes in values regarding umbilical artery pulsatility index and fetal heart rate values had a negative correlation (p < 0.0001). Finally, the middle cerebral artery pulsatility index significantly decreased (p < 0.001) from zero hours to after two hours of testing.

Attend this session to see what else the team found.

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