Monday, December 2 | 8:00 a.m.-8:10 a.m. | M1-SSBR04-1 | Room S406A
The impact of screening mammography versus clinical mode of detection on mortality will be explored in this presentation.
In his talk, Steven Chen will present results showing lower risk mortality associated with screening-detected breast cancers compared with clinically detected cancers. The research team also found that women of non-Hispanic ethnicity and with a family history of breast cancer who participated in cervical and colon cancer screening are more likely to have breast cancers found during routine mammography.
While screening mammography reduces breast cancer deaths. Chen et al noted that little data exists on how the mode of breast cancer detection impacts patient outcomes. The researchers compared these outcomes and factors tied to breast cancer diagnosis by screening versus clinical symptoms using TriNetX, a global research network containing real-world aggregate electronic medical record data from 35 health institutions and 51 million patients around the world.
The study included data collected between 2000 and 2023 from 3,927 women with breast cancers and reported modes of detection.
Clinically detected breast cancers lead to higher mortality risk compared with screening-detected cancers (16.87% vs. 8.38%, respectively). This included an odds ratio (OR) of 2.22 (p < 0.0001).
Also, screening-detected breast cancers showed significant ties to the following factors: non-Hispanic/Latino ethnicity (OR, 0.57; p < 0.0001), family history of breast cancer (OR, 0.47; p < 0.0001), hyperlipidemia (OR, 0.67; p < 0.0001), postmenopausal status (OR, 0.39; p < 0.0001), uses of cervical cancer screening (OR, 0.41; p < 0.0001), colon cancer screening (OR, 0.52; p < 0.0001), and immunization (OR, 0.51; p < 0.0001).
Finally, the team found that history of stroke was associated with a higher risk of clinically detected breast cancer (OR, 1.68; p < 0.0001).
Attend this session to find out more. This presentation earned an RSNA Trainee Research Prize.
