Sunday, November 30 | 11:05 a.m.-11:15 a.m. | SSA01-03 | Arie Crown Theater
Four years after breast density notification legislation was enacted in Connecticut, the addition of screening breast ultrasound for women with dense tissue has continued to improve breast cancer detection compared with mammography alone, according to research to be presented on Sunday.The technology's positive predictive value doubled between year 3 and 4, noted Dr. Jean Weigert, from the Hospital of Central Connecticut, and colleagues.
Weigert's group investigated how breast ultrasound has continued to perform as a follow-up screening modality for women with dense tissue in the years since the law was passed. The researchers used data from two Connecticut radiology practices with five sites.
A total of 32,230 screening mammograms and 4,128 dense-breast ultrasounds were performed in the third year after the legislation, and 27,937 screening mammograms and 3,330 dense-breast ultrasounds were performed in year 4. A third of the women eligible for screening ultrasound requested it, according to Weigert and colleagues.
The cancer detection rate in both the third and fourth years was three per 1,000 women -- the same rate as in the first two years after the law was enacted. But screening breast ultrasound's positive predictive value doubled from year 3 to year 4, from 8.1% to 16.1%, the team found.
















![Examples of ultrasound findings and techniques. (A) Images in a 39-year-old male patient with a mass in the left thigh. The mass is heterogeneous on the B-mode US image (compared with the patient in D) and showed increased microvascularity (superb microvascular imaging [SMI]) and shear-wave elastography (SWE) values. Undifferentiated pleomorphic sarcoma was diagnosed at biopsy (with pleomorphic rhabdomyosarcoma in surgical specimen). (B) Images in an 18-year-old male patient with a mass in the left leg. The mass is hypoechoic on the B-mode image, with no other findings suggestive of malignancy. The lesion is in contact with the cortex of the tibia, which is slightly irregular. CT revealed a doubtful anteromedial tibial erosion. The microvascular study demonstrated high vascularization, suggestive of malignancy. Periosteal Ewing sarcoma was diagnosed with both histologic and immunohistochemical confirmation. (C) Images in a 69-year-old female patient with a lump growing on the outside of the left leg. Multiple SWE examinations were performed (please note the high values obtained in the measurements, whereas the color map highlights the stiffness relative to adjacent tissues). SMI showed areas of increased vascularization to target for sampling. Undifferentiated spindle cell sarcoma was diagnosed at biopsy, with residual leiomyosarcoma in the surgical specimen after neoadjuvant therapy. (D) Images in a 56-year-old female patient with a mass in the right thigh. The mass is heterogeneous at both B-mode ultrasound (similar to patient A) and MRI (coronal T2-weighted spectral attenuated inversion recovery [SPAIR]; T1-weighted pre-contrast and postcontrast imaging), which even shows uptake after the administration of paramagnetic contrast material, which is traditionally suggestive of malignancy. Low values at SMI and elastography are suggestive of benignity. Spindle cell lipoma was diagnosed at biopsy, with atypical spindle cell lipomatous tumor in the surgical specimen.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/08/images-radiol250278fig2.APCFLSvX6p.jpg?auto=format%2Ccompress&fit=crop&h=112&q=70&w=112)


