Molecular Imaging

New theranostics PET tracer shows promise
By Will Morton
A new gallium-68 (Ga-68) PET/CT radiotracer appears superior over F-18 FDG for detecting bone metastases.
April 17, 2025
Images of a 69-year-old man diagnosed with prostate cancer who had a history of endocrine therapy for two years. (a) The maximum intensity projection (MIP) image of F-18 FDG showed moderate radiotracer uptake in a thoracic vertebra. (e) The MIP image of Ga-68 DOTA-IBA demonstrated more lesions in the cervical vertebra and pelvis. (b) An osteoblastic lesion in the C3 vertebra right attachment (curved arrows) was negative on F-18 FDG (SUVmax = 2.0) and positive on Ga-68 DOTA-IBA (SUVmax = 8.7). (c) Another osteoblastic lesion in the T10 vertebra left side (arrowheads) was both positive on F-18 FDG (SUVmax = 5.2) and positive on Ga-68 DOTA-IBA (SUVmax = 35.0). (d) Osteoblastic lesions in bilateral ilium (dotted arrows and arrows) were negative on F-18 FDG (left: SUVmax = 1.4, right: SUVmax = 1.6) and positive on Ga-68 DOTA-IBA (left: SUVmax = 7.6, right: SUVmax = 8.7). Follow-up imaging three months later confirmed the presence of these bone metastases. Image and caption available for republishing under Creative Commons license (CC BY 4.0 DEED, Attribution 4.0 International) and courtesy of Scientific Reports.
PET/CT detects vasculitis following COVID-19 vaccination
By Will Morton
A whole-body F-18 FDG-PET/CT scan was key in identifying medium-vessel vasculitis in a patient following a Moderna COVID-19 vaccination.
April 11, 2025
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PET links depressive symptoms to Alzheimer’s brain pathology
By Will Morton
Researchers have reported that worsening depression in older adults is related to higher levels of Alzheimer’s pathology.
April 10, 2025
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IMV: PET procedure volumes continue strong growth trend
By Davin Korstjens
Overall PET procedure volumes increased by 12.2% in 2024, according to the IMV 2025 PET Market Summary Report.
April 10, 2025
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Having a father with Alzheimer's could mean higher risk of the disease
By Kate Madden Yee
Having a father with Alzheimer's may be tied to a greater spread of the tau protein in the brain, researchers have reported.
April 9, 2025
Alzheimers Tau
PET reveals brain’s responses to music
By Will Morton
PET has provided the first neuroimaging evidence that music affects the brain’s opioid receptor system.
April 7, 2025
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China limits exports of rare earth elements, targets CT x-ray tubes
By Erik L. Ridley
China's Ministry of Commerce has announced export controls for several rare earth elements and launched investigations of imported CT x-ray tubes.
April 4, 2025
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SPECT/CT measure validated for diagnosing ATTR
By Will Morton
A research team in Finland has validated the accuracy of a SPECT/CT measure for diagnosing transthyretin amyloidosis.
April 4, 2025
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CAC score of 0 indicate low heart event risk, even in older people
By Kate Madden Yee
PET/CT imaging indicates that a coronary artery calcium (CAC) score of 0 is an accurate indicator of low coronary heart event risk even as a person ages, investigators have reported.
March 29, 2025
Heart Plaque
PET/CT visualizes extremely rare brain inflammation
By Will Morton
An F-18 FDG-PET/CT scan proved crucial in identifying an ultrarare case of brain inflammation in a patient due to the flu.
March 27, 2025
Brain MRI and F-18 FDG brain and whole-body PET/CT images. (A) No obvious abnormalities were found in axial and sagittal slices from T2-weighted MR images. (B) Whole cerebellar cortex had diffuse F-18 FDG hypermetabolism in PET/CT brain images, with SUVmax of 25.91. (C and D) Whole-body F-18 FDG-PET/CT showing distended bladder. TLG = total lesion glycolysis; MTV = metabolic tumor volume. Image and caption courtesy of the Journal of Nuclear Medicine.
Targeted alpha therapy’s ‘elite 8’ radionuclides
By Will Morton
A select group of eight radionuclides holds hopes for an emerging cancer treatment in nuclear medicine called targeted alpha therapy (TAT).
March 26, 2025
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New method proposed for diagnosing Alzheimer’s
By Will Morton
Researchers in Germany have proposed a new approach derived from brain PET imaging for diagnosing and staging Alzheimer’s disease.
March 25, 2025
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