Dr. Kristy Wolfel

Breast
Adenopathy may occur after COVID-19 vaccination
As COVID-19 vaccinations become readily available, mammographers must be alert for the possibility that a recent COVID-19 vaccination may be responsible for patients with unilateral axillary adenopathy. Radiologist Dr. Kristy Wolfel explains what to look out for.
March 9, 2021
2021 03 09 21 07 2400 Wolfel Kristy
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How can AI best help in LDCT lung cancer screening?
A commercially available AI-based tool appears effective as a prescreener in low-dose CT lung cancer screening.
Images of a 69-year-old man diagnosed with prostate cancer who had a history of endocrine therapy for two years. (a) The maximum intensity projection (MIP) image of F-18 FDG showed moderate radiotracer uptake in a thoracic vertebra. (e) The MIP image of Ga-68 DOTA-IBA demonstrated more lesions in the cervical vertebra and pelvis. (b) An osteoblastic lesion in the C3 vertebra right attachment (curved arrows) was negative on F-18 FDG (SUVmax = 2.0) and positive on Ga-68 DOTA-IBA (SUVmax = 8.7). (c) Another osteoblastic lesion in the T10 vertebra left side (arrowheads) was both positive on F-18 FDG (SUVmax = 5.2) and positive on Ga-68 DOTA-IBA (SUVmax = 35.0). (d) Osteoblastic lesions in bilateral ilium (dotted arrows and arrows) were negative on F-18 FDG (left: SUVmax = 1.4, right: SUVmax = 1.6) and positive on Ga-68 DOTA-IBA (left: SUVmax = 7.6, right: SUVmax = 8.7). Follow-up imaging three months later confirmed the presence of these bone metastases. Image and caption available for republishing under Creative Commons license (CC BY 4.0 DEED, Attribution 4.0 International) and courtesy of Scientific Reports.
Molecular Imaging
New theranostics PET tracer shows promise
Ultrasound images depict a 56-year-old man with obesity (body mass index, 42) and steatosis (MRI-PDFF, 10.4%), who underwent ultrasound attenuation coefficient (AC) measurement due to participation in the present study. The unit displays color-coded confidence map (left) and AC map (on right) in side-by-side manner. The confidence map indicates quality of acquired AC signals and is set like traffic lights: green indicates good quality acquisition, yellow indicates warning, and red indicates low quality. Areas with low quality are left blank on the AC map. The image shows multiple circular ROIs placed at depths below the liver capsule of 2, 2.5, 3, and 4 cm. All ROIs are 3.5 cm in size. The confidence map threshold is set at 20%. AC measurements (in units of dB/cm/MHz) were extracted from all ROIs (excluding voxels without assigned color on the AC map) and decrease with greater ROI depth.
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Images of a 69-year-old man diagnosed with prostate cancer who had a history of endocrine therapy for two years. (a) The maximum intensity projection (MIP) image of F-18 FDG showed moderate radiotracer uptake in a thoracic vertebra. (e) The MIP image of Ga-68 DOTA-IBA demonstrated more lesions in the cervical vertebra and pelvis. (b) An osteoblastic lesion in the C3 vertebra right attachment (curved arrows) was negative on F-18 FDG (SUVmax = 2.0) and positive on Ga-68 DOTA-IBA (SUVmax = 8.7). (c) Another osteoblastic lesion in the T10 vertebra left side (arrowheads) was both positive on F-18 FDG (SUVmax = 5.2) and positive on Ga-68 DOTA-IBA (SUVmax = 35.0). (d) Osteoblastic lesions in bilateral ilium (dotted arrows and arrows) were negative on F-18 FDG (left: SUVmax = 1.4, right: SUVmax = 1.6) and positive on Ga-68 DOTA-IBA (left: SUVmax = 7.6, right: SUVmax = 8.7). Follow-up imaging three months later confirmed the presence of these bone metastases. Image and caption available for republishing under Creative Commons license (CC BY 4.0 DEED, Attribution 4.0 International) and courtesy of Scientific Reports.
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