Radiology 2001 May;219(2):503-9
Frequency and CT findings of recurrent disease after lung
transplantation.
Collins J, Hartman MJ, Warner TF, Muller NL, Kazerooni EA, McAdams HP, Slone RM, Parker
LA.
PURPOSE: To determine the frequency and computed tomographic (CT) findings of recurrence
of the primary disease after lung transplantation at six North American lung
transplantation centers. MATERIALS AND METHODS: Medical records of 1,394 lung transplant
recipients were reviewed to identify patients with recurrent primary disease. Their CT
scans and pathologic specimens were reviewed. RESULTS: The frequency of disease recurrence
in the six transplantation centers was 1% (15 of 1,394 patients), including six previously
reported cases. Sarcoidosis recurred in nine (35%) of 26 transplants and was the most
common disease to recur. Three (33%) of nine patients with recurrent sarcoidosis had
correlative findings at CT. When present, CT findings were usually different at recurrence
compared with pretransplantation CT findings. CONCLUSION: A relatively small percentage of
patients are at risk for recurrence of primary disease following lung transplantation.
Sarcoidosis is the most common disease to recur.
