J Reprod Med 1999 Sep;44(9):775-8
Whole-body PET with (fluorine-18)-2-deoxyglucose for detecting recurrent
ovarian carcinoma. Initial report.
Yuan CC, Liu RS, Wang PH, Ng HT, Yeh SH.
OBJECTIVE: To investigate positron emission tomography (PET) with
(fluorine-18)-2-deoxyglucose (FDG) for detecting recurrent ovarian carcinoma.
STUDY DESIGN: Wholebody FDG-PET scanning was performed on five patients before
surgical exploration. All five patients were suspected of having recurrence
based upon clinical findings and underwent surgery after scanning. RESULTS: In
all five patients, PET images demonstrated increased FDG uptake in a
distribution that correlated with surgical-pathologic findings (100%); computer
tomography can detect 60% of such patients with malignant disease. Two cases
with unexplained elevated serum CA-125 had lesions localized by PET. CONCLUSION:
Recurrence of ovarian carcinoma was clearly imaged with FDG-PET and was
confirmed by surgical pathology. FDG-PET might be a fairly effective tool for
detecting recurrent ovarian carcinoma.
