Researchers from the Medical University of South Carolina and the University of Groningen in the Netherlands reviewed the imaging data of 81 patients with coronary artery disease (CAD) who underwent both coronary CT angiography (CCTA) and stress dynamic CT myocardial perfusion at one of four institutions. They used FFR-CT and myocardial blood-flow measurements from these data to estimate the prognostic value of the two imaging modalities.
Both FFR-CT and CT perfusion had a higher area under the curve for predicting major adverse cardiac events, with blood-flow measurements from CT perfusion providing the most accurate predictions. Combining the information from the two techniques further improved their predictive value, compared with using either of the techniques alone.
"Dynamic CT perfusion has the highest predictive value for major adverse cardiac events," doctoral candidate Marly van Assen told AuntMinnie.com. "Both FFR-CT and CT perfusion have added value in the prognostication of major adverse cardiac events and could provide complementary information."
