Resting-state fMRI circumvents brain lesion dilemma

Monday, November 27 | 11:50 a.m.-12:00 p.m. | SSC11-09 | Room N229
Can functional MRI (fMRI) still be effective when brain lesions create morphological distortion and patients are unable to perform tasks during scans? Researchers from NYU Langone Medical Center have found that resting-state fMRI can be used as an option to identify sensorimotor networks.

In a retrospective study of 29 patients with brain tumors who underwent fMRI for mapping, the researchers performed an analysis in the medial area and lateral precentral gyrus and in the posterior superior frontal gyrus of each hemisphere.

Using resting-state fMRI, the group identified complete sensorimotor networks in 44% of the patients, as well as key regions, including the left primary sensorimotor cortex, right primary sensorimotor cortex, and left supplementary motor area, in various subjects. The researchers created correlation maps of those networks and regions for a majority of the patients.

Dr. Rajan Jain, an associate professor of radiology and neurosurgery at NYU Langone, is scheduled to present the results.

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