Proton therapy succeeds in treating prostate cancer

Proton therapy yields long-term patient survival and excellent quality of life for prostate cancer patients, according to a study from the University of Florida Proton Therapy Institute.

A team led by Medical Director Dr. Nancy Mendenhall reported that 99% of men with early- and intermediate-risk prostate cancer were cancer-free five years after having proton therapy. Results were published in the International Journal of Radiation Oncology, Biology, Physics (March 2014, Vol. 88:3, pp. 596-602).

In addition, more than three-quarters of those with high-risk prostate cancer were free of disease at five years, according to the researchers.

The researchers tracked 211 patients, who were given proton therapy over an eight-week period.

Outcomes following proton therapy
  Low-risk patients Intermediate-risk patients High-risk patients
Cancer-free survival rate at 5 years 99% 99% 76%
Overall survival rate at 5 years 93% 88% 90%

Only 1.4% of patients had serious gastrointestinal complications, while 5.3% had serious urologic complications. Patients also reported good outcomes with respect to both urologic and bowel function, according to the group.

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