Dr. Wendie Berg, PhD, and colleagues will present results from a study they conducted using data from the American College of Radiology Imaging Network (ACRIN) 6666 trial to determine sources of false-negative mammography, sonography, and MRI -- in particular, whether these errors were caused by bad image quality or errors in interpretation.
Berg's team asked three breast imaging radiologists to review breast imaging performed the year before diagnosis and the year of diagnosis for each of 130 malignant lesions in 110 women in the ACRIN 6666 trial. The reviewing radiologists recorded various factors that affected lesion detection, including technical, detection, and interpretation issues.
The group found that errors in interpretation of screening ultrasound were similar in prevalence (21% of misses) to errors in mammographic (28% misses) and MRI interpretation (20% misses).