Swedish life sciences firm Biotage and McMaster University of Hamilton, Ontario, have inked a two-year extension to their molecular imaging development pact.
In the first year of the research deal, McMaster researchers employed Biotage's Initiator microwave synthesis system to prepare a range of carborane cage structures labeled with rhenium and technetium. They were able to achieve an 85% reduction in synthesis time and a 26% gain in decay-corrected yield compared with traditional synthesis methods, according to Biotage and McMaster.
In the second phase of the research, investigators will expand microwave synthesis to a broader range of radionuclides and probes used in PET imaging and as therapeutic agents, according to Uppsala-based Biotage.
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