IBA celebrates sale of the 100th Cyclone Kiube cyclotron

AuntMinnie.com staff writers

Dec 21, 2023

Belgium-based company Ion Beam Applications (IBA) is highlighting its milestone of the sale of the 100th Cyclone Kiube cyclotron, sold to Herlev Hospital, University of Copenhagen, in Denmark.

The cyclotron reaches up to 300 µA proton current. It includes a range of PET radioisotopes production, including fluorine-18 (F-18), gallium-68, zirconium-89, carbon-11, and others used in oncology, cardiology, and neurology imaging. The cyclotron is being used in 40 countries, IBA said.

$ChatGPT powered by GPT-4 and using DALL-E−3 was asked to generate an image for teaching purposes that demonstrated: a nuclear medicine bone scan with skeletal metastases (top left); coronary artery disease (top right); an F-18 FDG-PET scan of the brain with Alzheimer's disease (bottom left); and an x-ray showing a fracture (bottom right). These are misleading for educational purposes and for patients who may be searching for information. Image and caption courtesy of Radiography.$

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Team members from the theranostics clinic under University of Texas Health Science Center at San Antonio's Department of Radiology show one aspect of a Pluvicto infusion treatment. The L block lead shield over the syringe helps protect certified nuclear medicine technologist James Johnson (left), and nuclear radiologist Penny Vroman, MD (right), from radiation emitted by the drug. (Photo courtesy of UT Health San Antonio Department of Radiology)

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ChatGPT powered by GPT-4 and using DALL-E−3 was asked to generate an image for teaching purposes that demonstrated: a nuclear medicine bone scan with skeletal metastases (top left); coronary artery disease (top right); an F-18 FDG-PET scan of the brain with Alzheimer's disease (bottom left); and an x-ray showing a fracture (bottom right). These are misleading for educational purposes and for patients who may be searching for information. Image and caption courtesy of Radiography.

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Theranostics with Thomas Hope, MD, University of California, San Francisco (UCSF)

SNMMI to tackle Capitol Hill

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The Society of Nuclear Medicine and Molecular Imaging (SNMMI) will host its annual Hill Day on April 5 in Washington, DC.

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The rise of theranostics: Part 1 -- Gaining momentum

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March 26, 2024

Team members from the theranostics clinic under University of Texas Health Science Center at San Antonio's Department of Radiology show one aspect of a Pluvicto infusion treatment. The L block lead shield over the syringe helps protect certified nuclear medicine technologist James Johnson (left), and nuclear radiologist Penny Vroman, MD (right), from radiation emitted by the drug. (Photo courtesy of UT Health San Antonio Department of Radiology)

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Neiman HPI publishes advanced imaging prediction index

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2018 08 14 19 14 9213 Neiman Hip 400

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Representative Ga-68 FAPI-PET/CT images of 48-year-old woman who had left invasive ductal carcinoma and who achieved pathologic complete response (pCR). (A) Baseline maximum-intensity projection (MIP) image demonstrated primary lesion (red arrowhead; SUVmax, 26.72) and Ga-68 FAPI-avid lymph node in left axilla (red arrows). (B) MIP image after two cycles of neoadjuvant chemotherapy (NAC) showed that primary lesion (red arrowhead; SUVmax, 8.87) and axillary lymph nodes (red arrow) were reduced in size and radioactivity uptake. (C and D) Representative images of lab tissue staining for FAP before NAC showed strong FAP-positive staining in stromal cells (C), which was significantly decreased on tumor bed after six cycles of NAC (D). Image courtesy of the Journal of Nuclear Medicine.

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Nine representative patients who underwent F-18 FDG and F-18 FAPI-74 PET imaging. F-18 FAPI-74 PET outperforms F-18 FDG-PET in detecting primary tumors (patients 11, 39, 50, 58, 79, and 101; solid black arrows), local recurrences (patient 4; blue arrows), abdomen LN metastases (patients 4 and 50; green arrows), intrahepatic metastases (patient 50; red arrows), bone metastases (patient 85; arrowheads), and peritoneal metastases (patients 4, 11, 85, 97, and 101; dotted arrows). Image courtesy of the Journal of Nuclear Medicine.

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Researchers offer hypothesis for long COVID brain fog

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October 19, 2023

Hypometabolism detected with F-18 FDG-PET in long-COVID patients: putative astrocyte dysfunction and glutamatergic dysregulation. (A) PET scan of a healthy subject. (B) PET scan of a long COVID patient. Hypometabolic areas are indicated with arrows. (C) A diagram showing a healthy condition in which an astrocyte has a normal capacity to take up glutamate and recycle it to sustain glutamatergic neurotransmission, giving rise to normal glucose utilization and lactate production to ensure adequate neuronal energy supply. (D) A diagram showing a long COVID condition in which an astrocyte has reduced glutamate uptake capacity, leading to reduced glutamate recycling, lower glucose utilization (observed with F-18 FDG-PET as hypometabolism) and lower lactate production, dysregulating glutamatergic neurotransmission, and possibly endangering neuronal survival.

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