Clinical News

Advanced ultrasound techniques improve soft tissue tumor evaluation
By Amerigo Allegretto
Both SWE and SMI can help distinguish benign from malignant soft tissue tumors.
August 26, 2026
Examples of ultrasound findings and techniques. (A) Images in a 39-year-old male patient with a mass in the left thigh. The mass is heterogeneous on the B-mode US image (compared with the patient in D) and showed increased microvascularity (superb microvascular imaging [SMI]) and shear-wave elastography (SWE) values. Undifferentiated pleomorphic sarcoma was diagnosed at biopsy (with pleomorphic rhabdomyosarcoma in surgical specimen). (B) Images in an 18-year-old male patient with a mass in the left leg. The mass is hypoechoic on the B-mode image, with no other findings suggestive of malignancy. The lesion is in contact with the cortex of the tibia, which is slightly irregular. CT revealed a doubtful anteromedial tibial erosion. The microvascular study demonstrated high vascularization, suggestive of malignancy. Periosteal Ewing sarcoma was diagnosed with both histologic and immunohistochemical confirmation. (C) Images in a 69-year-old female patient with a lump growing on the outside of the left leg. Multiple SWE examinations were performed (please note the high values obtained in the measurements, whereas the color map highlights the stiffness relative to adjacent tissues). SMI showed areas of increased vascularization to target for sampling. Undifferentiated spindle cell sarcoma was diagnosed at biopsy, with residual leiomyosarcoma in the surgical specimen after neoadjuvant therapy. (D) Images in a 56-year-old female patient with a mass in the right thigh. The mass is heterogeneous at both B-mode ultrasound (similar to patient A) and MRI (coronal T2-weighted spectral attenuated inversion recovery [SPAIR]; T1-weighted pre-contrast and postcontrast imaging), which even shows uptake after the administration of paramagnetic contrast material, which is traditionally suggestive of malignancy. Low values at SMI and elastography are suggestive of benignity. Spindle cell lipoma was diagnosed at biopsy, with atypical spindle cell lipomatous tumor in the surgical specimen.
CT reveals progressive growth pattern in incidental lung nodules
By Will Morton
This pattern is most associated with a family history of lung cancer.
August 25, 2026
Serial axial chest CT scans demonstrating the longitudinal evolution of small pure ground-glass nodules (pGGNs) incidentally detected during a routine wellness assessment. (A) Images in a 37-year-old woman with a family history of lung cancer show a nodule with the progressive growth pattern (box). The baseline CT scan, obtained in October 2017, demonstrates a pure ground-glass nodules in the right lower lobe. Consecutive CT scans obtained from 2017 to 2022 show the continuous enlargement of the nodule during active surveillance. The maximum diameter of the nodule increased from 5.6 mm in 2017 to 10.2 mm in 2022. (B) Images in a 45-year-old man show a nodule with the indolent growth pattern (box). The baseline CT scan, obtained in April 2018, demonstrates a pure ground-glass nodules in the left lower lobe. Consecutive CT scans obtained from 2019 to 2023 show that the nodule remained radiographically stable during CT surveillance. The maximum diameter of the nodule was 5.4 mm in 2018 and 6.1 mm at the final surveillance scan in 2023.
Thymic health should be considered for radiotherapy planning
By Amerigo Allegretto
New evidence shows that unintended radiation exposure to the thymus during lung cancer treatment may lead to worse outcomes.
August 26, 2026
Radiation Treatment Cancer 400 (2)
Podcast: Where do MRI accident reports go?
By Liz Carey
MRI insiders quickly learned about the 2023 MRI accident in which a nurse was pinned to an MRI scanner by an ICU bed.
August 25, 2026
The Invisible Force Podcast Album Cover Auntminnie Jan 2026 Thumbnails
MRI detects ARIA in 21% of real-world donanemab patients
By Will Morton
Of the 48 patients who underwent at least one surveillance MRI, 10 (21%) had an ARIA detected.
August 24, 2026
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What independent clinics need to know before buying a CT scanner
By Joe Mason, Brandon Bush
In a new column, Brandon Bush and Joe Mason of Arineta offer CT purchasing advice for independent practices.
August 24, 2026
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Radiotherapy access could address gynecological cancer disparities
By Amerigo Allegretto
Inadequate radiotherapy infrastructure is one of several drivers of gynecological cancer disparities in LMICs.
August 24, 2026
Radiotherapy 400
Food insecurity linked to higher risk of death in breast cancer
By Will Morton
Food-insecure regions are where people lack consistent access to enough affordable, nutritious food.
August 21, 2026
Food Insecurity
How much surveillance imaging is needed for meningiomas?
By Amerigo Allegretto
Most surveillance MRI or CT exams did not result in intervention, and treatment rates remained stable during the study period.
August 21, 2026
Mri Slide 400
Ultrasound MinnieCast, Episode 15: Wearable ultrasound making strides
By Amerigo Allegretto
Geonho (Tom) Park, PhD, from Stanford Medicine shares insights from the work he and colleagues have done in wearable ultrasound.
August 21, 2026
Minnie Cast Thumbnail (20)
PET/CT outperforms MRI after focal therapy for prostate cancer
By Will Morton
No accurate noninvasive method has been validated to evaluate treatment response after focal therapy.
August 20, 2026
True-positive PSMA-PET with positive MRI in 74-year-old male with prostate cancer (Gleason score of 4 + 5; left anterior and posterior apex positive cores). (A) Left posterior peripheral apical to midprostate hyposignal visible on transaxial MRI. (B) No definite CT correlate evident (white arrow). (C) Focal high PSMA expression detectable in left posterior mid to base with SUVmax of 12.4 on transaxial fused delayed pelvic PET/CT (yellow arrow). (D) Focal high PSMA expression found in left midgland to base of prostate on maximum-intensity-projection image (yellow arrow).
Thermal ablation achieves long-term survival in kidney cancer
By Will Morton
The 10-year overall survival (OS) and cancer-specific survival (CSS) rates were 68.5% and 75.5%.
August 20, 2026
Kidney2
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