Tracheal Squamous Cell Carcinoma:
Clinical:
Ninety percent of all adult primary tracheal tumors are malignant [3] and squamous cell carcinoma is the most common primary malignancy of the trachea [3] (45% of tracheal neoplasms). Most patients are between the ages of 50-60 years, men are affected 2 to 4 times as often as women, and there is a strong association with smoking. [3] The tumor can be exophytic or infiltrative and tends to involve the posterior wall of the lower two-thirds of the trachea [2]. When symptomatic, the tumor often occludes more than 50% of the airway diameter [3]. Nearly one-third of patients will have another respiratory tract malignancy and the tumor is multi-focal in about 10% of cases. Sputum cytology will be positive in about half the cases. The tumor spreads to regional lymph nodes and infiltrates locally. Tracheoesophageal fistula is noted in 15% of cases. Treatment is surgical when possible, and/or XRTREFERENCES:
(1) J Thorac Imag 1995; 10: 180-198
(2) Radiographics 2009; Park CM, et al. Tumors in the
tracheobronchial tree: CT and FDG PET features. 29: 55-71
(3) AJR 2013; Ngo VH, et al. Tumors and tumorlike conditions of the large airways. 201: 301-313
