GE nets fluorescent imaging grant

GE Healthcare sister unit GE Global Research has received a four-year, $4 million grant from the U.S. National Institutes of Health (NIH) to develop a fluorescent nerve imaging agent and surgical system.

GE scientists have already developed an initial fluorescent imaging agent and a prototype optical imaging system to "light up" most nerves in the body, according to GE Global Research of Niskayuna, NY. The agent is a fluorescent small molecule that localizes to myelin, a major component of motor nerves and clinically important sensory nerves.

The goal is to help surgeons see delicate nerve endings that are prone to damage during procedures such as prostate surgery, the company said.

GE said its scientists have already optimized a prototype imaging system with a fluorescent imaging agent to localize to the margins of a tumor, aiming to provide a better chance of removing all of the cancer. The company believes that the nerve and tumor margin agents could one day be used together to show surgeons what tissue to remove, while also identifying sensitive areas such as nerves to avoid.

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