ITM, MTTI ink lutetium-177 supply deal

AuntMinnie.com staff writers

Apr 12, 2022

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ITM Isotope Technologies Munich's subsidiary ITM Medical Isotopes and biopharmaceutical company Molecular Targeting Technologies (MTTI) have signed a supply deal for no-carrier-added lutetium-177 (Lu-177).

ITM will provide Lu-177 to MTTI for the preclinical and clinical development and potential commercial production of MTTI's radiopharmaceutical candidate Lu-177 EBTATE to treat a range of cancers.

Currently, Lu-177 EBTATE is in clinical development for the treatment of neuroendocrine tumors, a special form of thyroid cancer, and nasopharyngeal cancer. The radiopharmaceutical is to be used in targeted radionuclide therapy, a precise approach to directly target and destroy tumor tissue with minimal effect on surrounding healthy tissue.

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New! Imaging Life Issue 20 now available

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Lesion uptake from a patient with a solitary fibrous tumor and its FAP expression on gallium-68 (GA-68)-FAPI-46 (A) and intratherpeutic Y-90-FAPI-46 (B). The panel shows the constructed time activity curve with the three PET/CT measurements.

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SNMMI: PET-based protocol shows promise in radioligand therapy

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A PET-based scout dosimetry protocol can be feasible in treating lesions with yttrium-90 FAPI (Y-90 FAPI) radioligand therapy.

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Lesion uptake from a patient with a solitary fibrous tumor and its FAP expression on gallium-68 (GA-68)-FAPI-46 (A) and intratherpeutic Y-90-FAPI-46 (B). The panel shows the constructed time activity curve with the three PET/CT measurements.

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Team members from the theranostics clinic under University of Texas Health Science Center at San Antonio's Department of Radiology show one aspect of a Pluvicto infusion treatment. The L block lead shield over the syringe helps protect certified nuclear medicine technologist James Johnson (left), and nuclear radiologist Penny Vroman, MD (right), from radiation emitted by the drug. (Photo courtesy of UT Health San Antonio Department of Radiology)

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Neiman HPI publishes advanced imaging prediction index

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