Optical imaging improves mammography's specificity

Monday, November 28 | 8:50 a.m.-9:00 a.m. | MSVM21-02 | Arie Crown Theater
In this Monday morning session, Boston researchers will describe how combining tomographic optical breast imaging with mammography or digital breast tomosynthesis (DBT) can improve specificity in the early diagnosis of breast cancer and reduce unnecessary biopsies.

Qianqian Fang, PhD, and colleagues from Massachusetts General Hospital and Harvard Medical School will present findings from a study conducted using a combined tomographic optical breast imaging/DBT imager they developed. The study included 51 patients who underwent scanning with the combined unit (of the 51 patients, 26 had malignant lesions, 17 had solid benign lesions, and eight had cysts).

Fang's team used a joint image reconstruction approach to guide the reconstruction of the functional optical images. The researchers found that these images with the structural priors showed more spatial details in the lesion compared with the results from non-prior-guided reconstructions, leading the group to conclude that the combined tomographic optical breast imaging/DBT imaging system could find cancer with higher sensitivity and specificity than mammography alone.

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