Lola Koktysh

MRI
Quantitative imaging biomarkers show promise for NASH
Quantitative imaging biomarkers are a promising approach for evaluating normal biological or pathogenic processes, as well as response to treatment and intervention. One near-term clinical application is the assessment of nonalcoholic steatohepatitis (NASH), according to Lola Koktysh of ScienceSoft.
March 6, 2017
2017 03 06 17 07 58 262 Man Liver 400
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Axial (A) and Coronal (B) CTPA show multiple partial intraluminal filling defects along the course of the right middle lobar segmental branches (medial segment) (yellow arrow) and lower lobar and postero-medial segmental branches (green arrow). Note the low-signal filling defects on the axial and coronal 0.55T MRI sequence.
ISMRM 2025
ISMRM: Contrast-free MR angiography comparable to CT for PE detection
University of Michigan researchers investigate detectability of pulmonary embolism by noncontrast MR angiography at 0.55 tesla.
Associations between insulin resistance and MWF. (A) Distribution of insulin resistance, stratified by sex. (B) Regression analysis of whole-brain MWF vs. log (HOMA-IR), adjusted for age and age². Shaded regions indicate 95% confidence intervals. (C) Regression analysis of whole-brain MWF vs. log (HOMA-IR), adjusted for age, age², sex, and log (HOMA-IR) sex. Graphics and caption courtesy of Nathan Zhang, PhD, and the ISMRM.
ISMRM 2025
ISMRM: Insulin resistance in women associated with less myelin, changes in brain
Representative T2-FLAIR, CBF maps, choroid plexus segment, free-water maps, ALPS ROI, and 3D T1BRAVO from a stroke patient, and a healthy control. Both individuals are 64 years old in chronological age. The patient displays an evident ischemic lesion in the basal ganglia region on T2-FLAIR imaging. The distinctions between the patient and the healthy control are as follows: CBF (32.22 ml/100g/min vs. 47.70 ml/100g/min), CPVF (1.47 vs. 0.84), VCSFVF (32.50 vs. 11.00), MSFW (0.0455 vs. 0.0313), ALPS (1.04 vs. 1.54), and BPAD (13.21 vs. -1.60).
ISMRM 2025
ISMRM: Brain’s waste-clearing system accelerates brain aging after stroke
Researchers at ISMRM highlighted the success of a trimodal MR-PET-FUS system built around a low-field MRI scanner. MR (top) and PET (bottom) images were acquired simultaneously before and after FUS heating.
ISMRM 2025
ISMRM: Trimodal PET-MR-FUS may be feasible therapy monitoring option
Protocol time and recall bounds as a function of AI specificity and sensitivity. On the top, the bounds are shown as a function of the specificity of the AI algorithm, for a fixed value of the sensitivity of that same AI model. On the bottom, the bounds are shown as a function of the sensitivity, for a fixed specificity. Graphics and caption courtesy of the ISMRM.
ISMRM 2025
ISMRM: Switching between full and short breast MRI reduces recalls
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ISMRM: Contrast-free MR angiography comparable to CT for PE detection
By Liz Carey
University of Michigan researchers investigate detectability of pulmonary embolism by noncontrast MR angiography at 0.55 tesla.
May 10, 2025
Axial (A) and Coronal (B) CTPA show multiple partial intraluminal filling defects along the course of the right middle lobar segmental branches (medial segment) (yellow arrow) and lower lobar and postero-medial segmental branches (green arrow). Note the low-signal filling defects on the axial and coronal 0.55T MRI sequence.
ISMRM: Insulin resistance in women associated with less myelin, changes in brain
By Maryam Payne
ISMRM research indicates that higher insulin resistance is associated with less myelin in women.
May 10, 2025
Associations between insulin resistance and MWF. (A) Distribution of insulin resistance, stratified by sex. (B) Regression analysis of whole-brain MWF vs. log (HOMA-IR), adjusted for age and age². Shaded regions indicate 95% confidence intervals. (C) Regression analysis of whole-brain MWF vs. log (HOMA-IR), adjusted for age, age², sex, and log (HOMA-IR) sex. Graphics and caption courtesy of Nathan Zhang, PhD, and the ISMRM.
ISMRM: Brain’s waste-clearing system accelerates brain aging after stroke
By Will Morton
The the brain’s glymphatic system appears to accelerate brain aging in patients after ischemic stroke.
May 10, 2025
Representative T2-FLAIR, CBF maps, choroid plexus segment, free-water maps, ALPS ROI, and 3D T1BRAVO from a stroke patient, and a healthy control. Both individuals are 64 years old in chronological age. The patient displays an evident ischemic lesion in the basal ganglia region on T2-FLAIR imaging. The distinctions between the patient and the healthy control are as follows: CBF (32.22 ml/100g/min vs. 47.70 ml/100g/min), CPVF (1.47 vs. 0.84), VCSFVF (32.50 vs. 11.00), MSFW (0.0455 vs. 0.0313), ALPS (1.04 vs. 1.54), and BPAD (13.21 vs. -1.60).
ISMRM: Trimodal PET-MR-FUS may be feasible therapy monitoring option
By Amerigo Allegretto
Researchers at ISMRM 2025 touted the success of a trimodal MR-PET-FUS system that could have applications for therapy monitoring.
May 10, 2025
Researchers at ISMRM highlighted the success of a trimodal MR-PET-FUS system built around a low-field MRI scanner. MR (top) and PET (bottom) images were acquired simultaneously before and after FUS heating.
ISMRM: Switching between full and short breast MRI reduces recalls
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Switching between abbreviated and full protocols for breast MRI can reduce exam time and lower recall rates.
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Protocol time and recall bounds as a function of AI specificity and sensitivity. On the top, the bounds are shown as a function of the specificity of the AI algorithm, for a fixed value of the sensitivity of that same AI model. On the bottom, the bounds are shown as a function of the sensitivity, for a fixed specificity. Graphics and caption courtesy of the ISMRM.
Beta-amyloid testing results have limited emotional impact for patients
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PET/MRI reveals how brain stimulation technique works
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PET/MRI scans have revealed the mechanism underlying a brain stimulation technique for treating neurological and psychiatric conditions.
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Radiologists play a crucial role in the care of patients with Marfan syndrome, a systemic connective tissue disorder.
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Whole-body PET shows how naloxone blocks opioids
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PET imaging has shown for the first time how the opioid overdose treatment naloxone blocks neuroreceptors throughout the body.
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Komen rails against proposed federal cuts to women's health program
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Susan G. Komen is warning of proposed federal budget cuts to a program that helps breast and cervical cancer patients get proper care.
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CT muscle metrics could help screen for sarcopenia
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ISMRM president outlines key highlights of the upcoming annual meeting in Honolulu
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ISMRM President Margaret Hall-Craggs, MD, spoke with AuntMinnie about the upcoming annual meeting in Honolulu.
May 8, 2025
Craggs
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