Lola Koktysh

MRI
Quantitative imaging biomarkers show promise for NASH
Quantitative imaging biomarkers are a promising approach for evaluating normal biological or pathogenic processes, as well as response to treatment and intervention. One near-term clinical application is the assessment of nonalcoholic steatohepatitis (NASH), according to Lola Koktysh of ScienceSoft.
March 6, 2017
2017 03 06 17 07 58 262 Man Liver 400
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Two cases of pathologically confirmed intrahepatic cholangiocarcinomas in 68-year-old male patients. In both cases (A-H, case 1; I-P, case 2), CT scans (B, F, case 1; J, N, case 2) revealed intrahepatic bile duct dilation and suspected nodular lesions. While F-18 FDG PET/CT (A, C, D, case 1; I, K, L, case 2) failed to demonstrate abnormal tracer uptake (SUVmax 3.5, TBR 1.3 in Case 1; SUVmax 2.6, TBR 1.2 in Case 2), F-18 FAPI-04 PET/CT (E, G, H, case 1; M, O, P, case 2 ) showed positive uptake in the nodular lesions (SUVmax 9.7, TBR 3.5 in Case 1; SUVmax 9.6, TBR 3.3 in Case 2). Image available for republishing under Creative Commons license (CC BY 4.0 DEED, Attribution 4.0 International) and courtesy of BMC Cancer.
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