Characteristics of studies included in the systematic review

May 6, 2009

				SFM		FFDM
Study	Location	Source population and eligible age group^*	Study type	Equipment and film	No. of women/No. of cancers	Digital system and viewing modality	No. of women/No. of cancers
Lewin et al, 2002	Colorado	Population-based screening program; eligible ages, ≥ 40 y (mean, 55.6 y)	Prospective paired design	GE DMR, Kodak Min-R 2000 film	6,736/33^†	GE Senographe 2000D, prototype two-monitor workstation, soft-copy reading	6,736/27^†
Yamada et al, 2004	Miyagi, Japan	Population-based screening program; eligible ages, ≥ 50 y	Prospective paired design	Siemens Mammomat 300 Nova (Mo/Mo, Mo/Rh, Ts/Mo), Kodak Min-R 2000 film	480/2^‡	GE Senographe 2000D (Mo/Mo, Rh/Rh, Mo/Rh), Kodak DryView 8610 laser image unit, hard-copy reading	480/2^‡
Skaane et al, 2005 (Oslo I)	Oslo, Norway	Population-based screening program; eligible ages, 50-69 y (mean, 58.2 y)	Prospective paired design	Siemens Mammomat 300 with 29 kV Mo/Mo, Kodak Min-R 2000 film with Min-R 2190 screen	3,683/30^§	GE Senographe 2000D in AOP mode, soft-copy reading	3,683/26^§
Pisano et al, 2005 (DMIST)	34 centers in the U.S. and Canada	Population-based screening programs; eligible ages NA (mean, 54.9 y; IQR: 47, 62)	Prospective paired design, random allocation of modality order	System routinely used in each center	42,760/174	Five different types of digital mammography with soft- and/or hard-copy reading	42,760/185
Skaane et al, 2007 (Oslo II)	Oslo, Norway	Population-based screening program; eligible ages 45-69 y (42% were ages 45-49 y)	Randomized trial, random allocation stratified by age	Siemens Mammomat 300, Kodak Min-R 2000 film and Min-R 2190 screens	Ages 45-49 y: 7,082/14; ages 50-69 y: 9,903/50	GE Senographe 2000D, soft-copy reading	Ages 45-49 y: 2,935/9; ages 50-69 y: 4,009/32
Del Turco et al, 2007	Florence, Italy	Population-based screening program; eligible ages, 50-69 y (47% ages 50-59 y)	Two concurrent retrospective cohorts, matched by age and reporting radiologist; allocation to screening modality mainly by residence	Siemens Mammomat 1000	14,385/84	GE Senographe 2000D, MammoReport workstation, soft-copy reading	14,385/104
Vigeland et al, 2008	Vestfold County, Norway	Population-based screening program (first prevalent two-year round); ages 50-69 y (mean: 59 y)	FFDM population: women who attended first prevalent round in Vestfold County; control population: historic database of SFM prevalent two-year round in other 18 counties	Siemens Mammomat 300/3000/3000 Nova; GE Senographe DMR, Senographe 800 T; Instrumentarium (Alpha/Diamond); Kodak films (Min-RE, Min-R 2000)	324,763/2,105	Two static Lorad Selenia units (Hologic), flat-panel selenium detectors with 70-µm pixel size, soft-copy reading	18,239/140
Vinnicombe et al, 2008	East London, England	Population-based screening program; ages, > 50 y (median, 58 y; IQR: 54, 64)	Retrospective cohort; allocation to screening modality mainly by area of residence	Two mobile Lorad M IV units	31,718/205^¶	Three GE Senographe DS units, one Lorad Selenia unit	8,475/58^¶

^*IQR = interquartile range, NA = not available.
^†6,736 screening mammograms among 4,489 women.
^‡No screening-detected cancers had occurred up to end of follow-up (the two cancers are diagnostic cases added to the study).
^§Includes 10 interval cancers and 16 screening-detected cancers in subsequent round (cancers diagnosed at the initial round: 28 at SFM, 23 at FFDM).
^¶31,718 screening mammograms among 31,385 women at SFM and 8,475 screening mammograms among 8,377 women at FFDM.
Table courtesy of the Radiological Society of North America.