J Nucl Med 1994 Nov;35(11):1797-801
Iodine-131 in breast milk following therapy for thyroid carcinoma.
Robinson PS, Barker P, Campbell A, Henson P, Surveyor I, Young PR.
This study evaluates breast milk secretion of 131I following therapeutic
administration of 4000 MBq of 131I-iodide during lactation. METHODS: Breast milk
131I activity concentration was measured over a 32-day period. Dosimetry
calculations were undertaken to estimate the period for discontinuation of
breast feeding and the equivalent dose to the breasts. RESULTS: To achieve an
infant effective dose < 1 mSv and an infant thyroid dose < 10 mSv, breast
feeding would need to be discontinued for at least 52 days. The estimated
equivalent dose to the breasts was 1.6 Gy. CONCLUSION: It is suggested that
131I-iodide administration is not undertaken during lactation and that breast
feeding is discontinued several days prior to administration.
