Thyroid 1994 Winter;4(4):501-5
Management of patients with differentiated thyroid cancer who have positive
serum thyroglobulin levels and negative radioiodine scans.
Clark OH, Hoelting T.
Most current evidence suggests that patients with papillary or follicular
thyroid cancer after total thyroidectomy who are Tg positive (Tg > or = 10 ng/mL)
and radioactive iodine scan negative warrant treatment with 100 mCi of 131I with
a follow up scan and Tg determination. If isolated focal metastatic deposits are
present they should be resected before treatment with radioiodine. Although some
physicians might recommend radioiodine treatment only for high risk patients, we
would recommend it for all patients with elevated serum Tg levels that increase
after TSH stimulation, or until further information becomes available to support
a different approach.
Publication Types:
- Review
