Biopharmaceutical firm Paion of Aachen, Germany, has inked a deal with Philips Medical Systems of Andover, MA, to use the multimodality vendor's brain perfusion CT software in clinical trials of desmoteplase, a drug under investigation for the treatment of stroke patients.
Philips' postprocessing brain perfusion CT software helps doctors discriminate between the core of an infarction -- the dead tissue -- and the ischemic penumbra, or the viable but inadequately perfused tissue. The software displays summary maps, including color maps of cerebral blood flow and volume, as well as mean transit time and time-to-peak, information that helps physicians decide which patients would benefit from reperfusion therapy.
Part of a new group of plasminogen activators, desmoteplase is a genetically engineered form of a clot-dissolving protein found in the saliva of the vampire bat Desmodus rotundus. Earlier clinical trials have shown desmoteplase to be helpful in treating patients up to nine hours after the occurrence of stroke symptoms. The Food and Drug Administration has given the drug fast-track status, according to Paion.
By AuntMinnie.com staff writers
November 10, 2004
Related Reading
Road to RSNA: Philips Medical Systems, November 9, 2004
Philips renews deal with Unfors, November 5, 2004
Fischer, Philips partner, October 15, 2004
Philips inks Marietta Memorial deal, October 14, 2004
Philips begins shipping new PET/CT scanner, October 14, 2004
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![Images show the pectoralis muscles of a healthy male individual who never smoked (age, 66 years; height, 178 cm; body mass index [BMI, calculated as weight in kilograms divided by height in meters squared], 28.4; number of cigarette pack-years, 0; forced expiratory volume in 1 second [FEV1], 97.6% predicted; FEV1: forced vital capacity [FVC] ratio, 0.71; pectoralis muscle area [PMA], 59.4 cm2; pectoralis muscle volume [PMV], 764 cm3) and a male individual with a smoking history and chronic obstructive pulmonary disorder (COPD) (age, 66 years; height, 178 cm; BMI, 27.5; number of cigarette pack-years, 43.2, FEV1, 48% predicted; FEV1:FVC, 0.56; PMA, 35 cm2; PMV, 480.8 cm3) from the Canadian Cohort Obstructive Lung Disease (i.e., CanCOLD) study. The CT image is shown in the axial plane. The PMV is automatically extracted using the developed deep learning model and overlayed onto the lungs for visual clarity.](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/03/genkin.25LqljVF0y.jpg?auto=format%2Ccompress&crop=focalpoint&fit=crop&h=112&q=70&w=112)



