Wayne Forrest

Nuclear Medicine
Can PET/MRI correlate tau with first responders' cognitive issues?
PET/MR images of tau deposits among emergency responders on 9/11 are concerning, but they fall short of a definitive link to dementia, according to research presented at the Society of Nuclear Medicine and Molecular Imaging's annual meeting in Vancouver, Canada.
June 20, 2022
2022 06 20 22 02 7065 2022 06 21 Snmmi Zhou Pet Mri Tau Dementia 20220620222021
Nuclear Medicine
FES-PET/CT can help detect breast cancer
F-18 fluoroestradiol (FES)-PET/CT can be useful in detecting clinically significant breast cancer, according to preliminary study results presented June 12 at the Society of Nuclear Medicine and Molecular Imaging annual meeting in Vancouver, Canada.
June 13, 2022
2022 06 13 23 22 4696 2022 06 14 Ulaner Breast Fes Pet Snmmi 400
Molecular Imaging
FDG-PET/MRI offers option for pediatric Hodgkin lymphoma
FDG-PET/MRI is a promising alternative to FDG-PET/CT for staging and gauging treatment response for Hodgkin lymphoma, with the benefit of less radiation to pediatric and adolescent patients, according to a study published online February 19 in the Journal of Nuclear Medicine.
March 4, 2021
2021 03 01 05 21 3363 2021 03 03 Fdg Pet Mri Hodgkins Pedx Jnm 20210301054746
Molecular Imaging
Flortaucipir-PET scans show near-term dementia risk
Imaging specialists who visually interpreted flortaucipir-PET images were able to determine a person's risk of progressing to Alzheimer's and mild cognitive impairment within the next 18 months in a recent study.
February 16, 2021
2021 02 16 23 38 3157 2021 02 16 Pet Alzheimers Jama Neuro 20210216233510
Molecular Imaging
Nano-MRI outduels PSMA-PET/CT for prostate cancer
Clinicians looking to accurately classify suspicious lymph nodes in prostate cancer patients could have another effective noninvasive option with a unique contrast-enhanced MR imaging technique, according to a study published online January 30 in the Journal of Nuclear Medicine.
February 4, 2021
2021 02 04 20 55 8044 2021 02 05 Nano Mri Psma Pet Ct Prostate Cancer 20210204205609
Molecular Imaging
PET shows aerobic exercise has little effect on amyloid
While aerobic exercise is good for the cardiovascular system, PET images show a weekly regimen of this activity does nothing to change the status of beta-amyloid buildup in older adults with elevated levels of the marker for Alzheimer's disease, according to a study published online January 14 in PLOS One.
January 19, 2021
2021 01 19 23 02 4162 Senior Exercise Bands 400
Molecular Imaging
PET/CT guidance offers valuable approach to lung biopsies
One optimum way to reduce inconclusive lung biopsy results and better detect malignancies is to use FDG-PET/CT for the image-guided procedure. Researchers from Brazil found that PET/CT had advantages over conventional CT guidance.
January 12, 2021
2021 01 11 17 44 3678 2020 01 15 Fdg Pet Ct Guided Lung Biopsies 20210111174926
Molecular Imaging
FDA makes history with approval of Ga-68 PSMA-11 PET
The U.S. Food and Drug Administration's (FDA) recent approval of a PET radiotracer that targets lesions positive for prostate-specific membrane antigen (PSMA) is not only a "quantum leap" for the diagnosis of prostate cancer in men but also sets a precedent for academic research.
December 17, 2020
2020 12 12 01 18 3612 2020 12 16 Ga68 Psma Pet Calais Ucla 20201212012727
Molecular Imaging
PET links poor air quality to presence of amyloid plaque
PET scans of older Americans have revealed a potential link between the quality of air they breathe and the presence of brain plaque linked to Alzheimer's disease, according to a study published online November 30 in JAMA Neurology.
December 3, 2020
2020 12 04 00 44 2605 Smokestack Pollution 400
Molecular Imaging
PET ties coronary blood flow to future adverse events
Using PET perfusion to gauge cardiac blood flow capacity, researchers have found that severely reduced coronary flow reserve is a key contributor to a greater risk of a major adverse cardiac event and death, according to a study published online November 18 in Cardiovascular Imaging.
November 19, 2020
2018 11 06 23 34 9504 Pet Scan Patient 400
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Scans in a 73-year-old man with biochemically recurrent prostate cancer (prostate-specific antigen level of 0.5 ng/mL) who underwent PET/CT with 9.4 mCi of F-18 piflufolastat and a second PET/CT examination with 8.1 mCi of copper 61-NODAGA (1,4,7-triazacyclononane,1-glutaric acid-4,7-acetic acid)–prostate-specific membrane antigen for imaging and therapy (Cu-61 PSMA I&T) 24 days apart, with no intervening therapy. Maximum intensity projection (MIP) images obtained (A) 1 hour after F-18 piflufolastat administration and (B) 1, (C) 2, and (D) 4 hours after Cu-61 PSMA I&T administration are shown. Physiologic uptake is seen in the lacrimal glands, salivary glands, liver, spleen, kidneys, ureters, and bladder. Pathologic uptake in pelvic nodal metastases is labeled with arrows. The F-18 piflufolastat PET/CT MIP image reveals two avid pelvic nodal metastases (arrows). Cu-61 PSMA I&T PET/CT scans demonstrate three avid pelvic nodal metastases on 1-hour and 2-hour images (arrows); five avid pelvic nodal metastases were suspected on the 4-hour image (arrows).
Molecular Imaging
Phase I trial reveals the potential of a new PSMA-PET tracer
The radiotracer detected more lesions in men with metastatic disease than F-18 piflufolastat.
Images depict a 50-year-old woman with a lesion detected during screening ultrasound. (A) Transverse and (B) longitudinal images reveal a 0.5-cm hypoechoic lesion (arrow) in the left breast. (C) Transverse color Doppler ultrasound image does not show an increase in vascularity. Two readers classified the lesion as a mass, whereas two others categorized it as a nonmass lesion, leading to its designation as a controversial nonmass lesion. Ultrasound-guided core needle biopsy and subsequent pathologic examination confirmed a nonproliferative breast change.
Womens Imaging
Radiologists can designate nonmass lesions on breast ultrasound
Coronavirus
MRI
Long COVID's neurological effects persist
Obesity Text2
MRI
MRI proves effective for tracking results of obesity interventions
Phpt
Molecular Imaging
TVR-PET/CT shows promise in primary hyperparathyroidism
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Phase I trial reveals the potential of a new PSMA-PET tracer
By Will Morton
The radiotracer detected more lesions in men with metastatic disease than F-18 piflufolastat.
December 9, 2025
Scans in a 73-year-old man with biochemically recurrent prostate cancer (prostate-specific antigen level of 0.5 ng/mL) who underwent PET/CT with 9.4 mCi of F-18 piflufolastat and a second PET/CT examination with 8.1 mCi of copper 61-NODAGA (1,4,7-triazacyclononane,1-glutaric acid-4,7-acetic acid)–prostate-specific membrane antigen for imaging and therapy (Cu-61 PSMA I&T) 24 days apart, with no intervening therapy. Maximum intensity projection (MIP) images obtained (A) 1 hour after F-18 piflufolastat administration and (B) 1, (C) 2, and (D) 4 hours after Cu-61 PSMA I&T administration are shown. Physiologic uptake is seen in the lacrimal glands, salivary glands, liver, spleen, kidneys, ureters, and bladder. Pathologic uptake in pelvic nodal metastases is labeled with arrows. The F-18 piflufolastat PET/CT MIP image reveals two avid pelvic nodal metastases (arrows). Cu-61 PSMA I&T PET/CT scans demonstrate three avid pelvic nodal metastases on 1-hour and 2-hour images (arrows); five avid pelvic nodal metastases were suspected on the 4-hour image (arrows).
Radiologists can designate nonmass lesions on breast ultrasound
By Amerigo Allegretto
Breast radiologists achieved moderate to substantial interreader agreement for classifying nonmass lesions on ultrasound.
December 9, 2025
Images depict a 50-year-old woman with a lesion detected during screening ultrasound. (A) Transverse and (B) longitudinal images reveal a 0.5-cm hypoechoic lesion (arrow) in the left breast. (C) Transverse color Doppler ultrasound image does not show an increase in vascularity. Two readers classified the lesion as a mass, whereas two others categorized it as a nonmass lesion, leading to its designation as a controversial nonmass lesion. Ultrasound-guided core needle biopsy and subsequent pathologic examination confirmed a nonproliferative breast change.
Long COVID's neurological effects persist
By Kate Madden Yee
Long COVID is typically defined as persistent symptoms beyond four weeks from onset of the illness.
December 9, 2025
Coronavirus
MRI proves effective for tracking results of obesity interventions
By Kate Madden Yee
MRI is a powerful tool to monitor skeletal muscle adaptations during lifestyle interventions for obesity, researchers noted.
December 8, 2025
Obesity Text2
TVR-PET/CT shows promise in primary hyperparathyroidism
By Will Morton
Gallium-68 trivehexin PET/CT was superior for identifying lesions over technetium-99m sestamibi SPECT.
December 8, 2025
Phpt
ACR talks BI-RADS version 2025 with AuntMinnie
By Amerigo Allegretto
ACR members discussed the need to release the latest version of BI-RADS and what changes breast radiologists can expect.
December 8, 2025
Acr Logo 2023 400
ACR's Ted Burnes talks advocacy in radiology with AuntMinnie
By Amerigo Allegretto
Ted Burnes from the American College of Radiology spoke with AuntMinnie on achievements in advocacy and what 2026 may bring.
December 8, 2025
Screenshot (91)
PiB-PET/CT detects subtypes in cardiac amyloidosis
By Will Morton
PiB-PET/CT shows strong promise as a next-generation diagnostic tool for cardiac amyloidosis.
December 5, 2025
Heart
HPI: 13.5B mL of contrast media administered from 2011 to 2024
By Kate Madden Yee
The findings are sobering, as contrast use contributes to environmental pollution.
December 5, 2025
Contrast Injector
AI ultrasound tool could reduce unnecessary biopsies by 60%
By Amerigo Allegretto
An AI tool could help reduce unnecessary breast biopsies, but should be used in conjunction with radiologist decision-making.
December 5, 2025
2025 12 05 Ai Decision Support Tool Ultrasound Thumbnail
3D CNN model estimates MACE risk from chest CT
By Kate Madden Yee
The algorithm appears effective at predicting major adverse cardiovascular events (MACE) even when applied to diverse patient groups.
December 5, 2025
Lung Ct Images
What is the role of AI quantitation of coronary plaque?
By Liz Carey
Tracking coronary artery calcium score alone is not enough, according to an RSNA presentation.
December 4, 2025
Rsna 2025 Welcome
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