Miscellaneous Findings on Gallium Scintigraphy:

Miscellaneous Findings on Gallium Scintigraphy:

Decreased hepatic uptake:

Severe hepatic parenchymal disease

Iron overload (Multiple transfusions): Results in saturation of transferrin binding sites with increased renal excretion of unbound Ga-67

Recent chemotherapy (within 24 hours, especially vincristine): Due to hepatotoxic effect. Reticuloendothelial cells are not affected, however, and a Tc-SC scan will be normal.

Secondary to increased bone uptake: Commonly seen in:

  • Leukemia
  • Elevated transferrin levels: Commonly secondary to multiple or recent blood transfusions

Persistent (beyond 24 hours) prominent renal activity:

  • Iron overload (Multiple Transfusions)
  • Lymphoma
  • Nephrotoxic drugs: Chemotherapeutic agents such as cytoxan and vincristine.
  • Hepatic failure
  • Vasculitis
  • Renal amyloidosis
  • Acute pyelonephritis- typically focal

Diffuse increased colonic activity :

  • Inflammatory conditions:
  • Ulcerative colitis/Crohn's
  • Pseudomembranous colitis
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