PET/CT detects causes of paraneoplastic neurological syndromes

Sunday, November 29 | 11:15 a.m.-11:25 a.m. | SSA18-04 | Room S505AB
Even with frequent conventional diagnostic procedures, the diagnosis of paraneoplastic neurological syndromes (PNS) can be challenging because the underlying tumor can go undetected. In this scientific session presentation, German researchers will discuss their use of PET/CT as a tool to discover suspected PNS.

PNS is the remote effect of cancer and can cause problems with the central and peripheral nervous system and muscles. Timely identification and precise localization of the tumor are critical for appropriate treatment.

In this study, PET/CT detected foci of increased FDG uptake in 10 of 46 patients, and in six cases, combined PET/CT identified the underlying disease. Four of the 10 cases (8.7%) were positive for PNS. PET/CT also helped to detect vasculitic and local metastatic disease in two other patients, whereas four cases were false positive.

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