Bracco molecular imaging subsidiary Blue Earth Diagnostics is directing attention to new research that found PET/CT imaging with its Axumin (fluciclovine F-18) PET radiopharmaceutical had a significant impact on management of patients with recurrent prostate cancer.
In a secondary analysis of the LOCATE and FALCON prospective clinical trials, researchers from the Washington University School of Medicine reported that Axumin PET/CT detected lesions in 85 (58%) of the 146 patients who had received a prescan plan for androgen deprivation therapy, according to Blue Earth. Of the 146, 93 (64%) had a change in their management plan following the exam.
Androgen deprivation therapy was avoided or delayed in 55 (59%) of the 93 patients whose management plan had changed. In addition, only 15 (25%) of the 60 patients originally planned for androgen deprivation therapy monotherapy were still due to receive that treatment plan after Axumin PET/CT imaging, according to Blue Earth.
The results were presented on September 23 at the Global Summit on Precision Diagnosis and Treatment of Prostate Cancer.
![A 53-year-old patient (patient number four) with a recurrent pituitary adenoma with extension of a cystic component of disease to the medial temporal lobe apparent on MRI (contoured in blue), and extension of disease to the left sphenoid bone and orbital apex apparent on [68Ga]Ga-DOTA-TATE (contoured in yellow).](https://img.auntminnie.com/mindful/smg/workspaces/default/uploads/2026/04/pituitary-tumor.QGsEnyB4bU.jpg?auto=format%2Ccompress&dpr=2&fit=crop&h=167&q=70&w=250)
