NorthStar, Convergent ink Ac-225 supply deal

AuntMinnie.com staff writers

Mar 8, 2022

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NorthStar Medical Radioisotopes and Convergent Therapeutics have entered into a supply agreement for the actinium-225 (Ac-225) medical radioisotope.

Under the deal, NorthStar's Ac-225, a radioactive alpha-particle emitter, will be used in Convergent's proprietary drug candidate, CONV 01-α. The drug is a monoclonal antibody conjugated with actinium-225.

The drug candidate is a major component of Convergent's peptide receptor radionuclide therapy (PRRT) technology. PRRT targets prostate-specific membrane antigen present in prostate cancer cells.

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New! Imaging Life Issue 20 now available

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Lesion uptake from a patient with a solitary fibrous tumor and its FAP expression on gallium-68 (GA-68)-FAPI-46 (A) and intratherpeutic Y-90-FAPI-46 (B). The panel shows the constructed time activity curve with the three PET/CT measurements.

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Intraarterial PRRT safe in patients with meningioma

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NNSA's Mo-99 program: A bumpy ride

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SNMMI: PET-based protocol shows promise in radioligand therapy

By Amerigo Allegretto

A PET-based scout dosimetry protocol can be feasible in treating lesions with yttrium-90 FAPI (Y-90 FAPI) radioligand therapy.

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Lesion uptake from a patient with a solitary fibrous tumor and its FAP expression on gallium-68 (GA-68)-FAPI-46 (A) and intratherpeutic Y-90-FAPI-46 (B). The panel shows the constructed time activity curve with the three PET/CT measurements.

The rise of theranostics: Part 3 -- What is a theranostics center?

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Part3 Riseof Thernaostics Cover

Can AI improve sustainability in nuclear medicine?

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ChatGPT powered by GPT-4 and using DALL-E−3 was asked to generate an image for teaching purposes that demonstrated: a nuclear medicine bone scan with skeletal metastases (top left); coronary artery disease (top right); an F-18 FDG-PET scan of the brain with Alzheimer's disease (bottom left); and an x-ray showing a fracture (bottom right). These are misleading for educational purposes and for patients who may be searching for information. Image and caption courtesy of Radiography.

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Theranostics with Thomas Hope, MD, University of California, San Francisco (UCSF)

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Team members from the theranostics clinic under University of Texas Health Science Center at San Antonio's Department of Radiology show one aspect of a Pluvicto infusion treatment. The L block lead shield over the syringe helps protect certified nuclear medicine technologist James Johnson (left), and nuclear radiologist Penny Vroman, MD (right), from radiation emitted by the drug. (Photo courtesy of UT Health San Antonio Department of Radiology)

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Neiman HPI publishes advanced imaging prediction index

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The Harvey L. Neiman Health Policy Institute (HPI) has developed and released a comorbidity index designed to help predict use of advanced imaging.

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