Advanced Magnetics gets U.S. patent

Contrast agent developer Advanced Magnetics has received a U.S. patent related to the company’s next-generation iron oxide technology, which could be used for either MR angiography contrast agents or for therapy products.

The company’s patent covers heat-stable colloidal iron oxides coated with reduced carbohydrates and carbohydrate derivatives, the Cambridge, MA-based company reported. The patent covers various aspects of the company’s core carbohydrate-coated iron oxide technology, including its product in development, ferumoxytol.

Ferumoxytol is in phase II clinical trials for use as an iron replacement therapeutic in patients with chronic kidney disease who are receiving erythropoietin therapy. The agent is also in phase II clinical trials for use as a contrast agent in MRA, and in exploratory studies for the imaging of vulnerable plaque. Phase III clinical trials for iron therapy and MRA are expected to begin in late 2003 or 2004, the firm said.

By AuntMinnie.com staff writers
July 31, 2003

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