Earlier diagnostics enables faster Alzheimer's treatment

Jun 1, 2023

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New advances in diagnostics can help detect Alzheimer's disease sooner, enabling patients to benefit from new treatments to slow down progression, said Quest Diagnostics Medical Director for Neurology Dr. Michael Racke in a video interview.

Hormone therapy linked to tau accumulation in older women

March 7, 2025

The future of theranostics is bright

The future of theranostics is bright

March 1, 2025

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FES-PET shows promise staging patients with low-grade breast cancer

March 4, 2025

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FAPI-PET/CT shows promise in gynecological cancers

March 3, 2025

Hormone therapy linked to tau accumulation in older women

A PET study reveals that women over the age of 70 who took menopausal hormone therapy more than a decade prior have faster brain tau accumulation.

March 7, 2025

Ac-225: From nuclear waste to cancer treatment

U.S. Department of Energy (DOE) efforts to dispose of spent nuclear waste left over from the Cold War has turned into a boon for supplies of actinium-225 (Ac-225).

March 5, 2025

FES-PET shows promise staging patients with low-grade breast cancer

F-18 fluoroestradiol (FES) PET may improve staging of grade 1 or 2 estrogen receptor-positive breast cancer compared with F-18 FDG-PET.

March 4, 2025

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FAPI-PET/CT shows promise in gynecological cancers

Fibroblast activation protein inhibitor (FAPI) PET/CT appears superior to FDG-PET/CT for imaging gynecological cancers.

March 3, 2025

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ECR: PET/MRI highly effective for detecting prostate cancer

Hybrid PET/MRI scans outperform either technique alone for identifying tumors in high-risk patients with suspected prostate cancer.

February 28, 2025

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PET/CT predicts relapse in patients with ovarian cancer

Pretreatment F-18 FDG-PET/CT scans may predict relapse in patients with advanced high-grade serous ovarian cancer.

February 24, 2025

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PET/CT reveals new infections in ICU patients

F-18 FDG-PET/CT is a valuable approach for diagnosing unknown infections in intensive care unit (ICU) patients.

February 21, 2025

There are several conceivable advantages of F-18 FDG PET/CT over conventional imaging. Image A and B showing an example of the distinctive capability of the F-18 FDG PET/CT. A shows a fusion image of F-18 FDG PET/CT and low-dose CT and B an high resolution chest CT of a patient with an Aspergillus infection. The suspected aspergilloma is concealed on the high resolution CT due to the lung fluids and consolidation. Image C and D (fusion image of F-18 FDG PET/CT and low-dose CT and low-dose CT only, respectively) are examples of the ability to image inflammation while no concurrent abnormalities are visualized, in this case prostatitis (red arrows). Image E, a maximized intensity projection of F-18 FDG PET, shows a patient with lung infections and multiple muscle abscesses after MRSA sepsis. This is an illustrative example of a relevant dissemination investigation. Image and caption available for republishing under Creative Commons license (CC BY 4.0 DEED, Attribution 4.0 International) and courtesy of Annals of Intensive Care.

PSMA-PET tracer performs well in clinical trial

PET/CT imaging with a new gallium-68-based prostate cancer radiotracer shows promise for detecting recurrent metastatic disease.

February 20, 2025

(A) Representative maximum-intensity projection and selected PET/CT images (fused, PET and CT only) of patient with metastatic prostate cancer at 1 hour after injection. (B and C) Low uptake of Ga-68 PSMA-R2 in salivary and submandibular glands is also demonstrated. (D) Images show heterogeneous uptake of Ga-68 PSMA-R2 with varying degrees of intensity in multiple spine bone lesions (vertebral sclerotic lesion with intense PSMA-R2 expression at its periphery indicated with red arrow). HU = Houndsfield unit; SUVbw = body-weight SUV. Images and caption courtesy of the Journal of Nuclear Medicine.

New PET tracer developed for breast cancer

A new PET radiotracer shows promise for diagnosing triple-negative breast cancer.

February 14, 2025

Ga-68 FZ-NR-1 PET/CT images and F-18 FDG PET/CT and PET/MRI images in representative nectin-4-positive TNBC patients. (A) PET/CT images and nectin-4 immunohistochemistry (IHC) staining of patient 1. Maximum-intensity projection (MIP) images and axial and coronal PET/CT images of Ga-68 FZ-NR-1 and F-18 FDG both showed high uptake in lung metastases (arrow). (B) PET/CT images and nectin-4 IHC staining of patient 2. MIP images and axial and coronal PET/CT images of Ga-68 FZ-NR-1 showed high uptake in recurrence of right breast cancer after surgery (arrow), and those of F-18 FDG PET/MRI showed high uptake. Image courtesy of the Journal of Nuclear Medicine.

Pluvicto safe in patients with impaired kidneys

Lu-177 prostate-specific membrane antigen-617 (Lu-177 PSMA-617, Pluvicto) may be safely delivered in patients with impaired renal function.

February 13, 2025

Dosimetry key in Lu-177 cancer therapy

Personalized medicine is rapidly evolving in cancer theranostics, with technology now available that allows clinicians to optimize doses of radiopharmaceuticals on an individual patient level, according to experts.

February 5, 2025

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PET/CT guides surgery for primary aldosteronism

PET/CT imaging with gallium-68 pentixafor can effectively guide surgery for patients with primary aldosteronism, a common cause of hypertension.

January 30, 2025

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