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Coxiella burnetii pneumonia: Q Fever

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Clinical:

Q fever is a zoonosis caused by Coxiella burnetii - an obligate intracellular bacteria living in the phagosomes of the host cells. It can be found in the urine, feces, and milk of infected animals (especially cattle, sheep, and goats). C. burnetti can survive for long periods of time in the environment. Humans acquire the infection from inhaled dust or by ingesting unpasteurized milk or cheese. Farmers and stock breeders are at high risk becasue of contact with livestock. Clinical findings include prolonged fever, pneumonia, granulomatous hepatitis, and meningoencephalitis. Treatment is with tetracycline.

Chronic Q fever can develop in 1-5% of infected patients and it's manifestations include endocarditis, infected aneurysms, or infected vascular prostheses [3].

X-ray:

The most common radiographic finding is unilateral segmental or lobar consolidations. The consolidation can appear mass-like. Pleural effusion can be found in about 15% of cases. The most common finding on CT scan is multilobar air space consolidation [2].

REFERENCES:
(1) Radiology 1999; Gikas A, et al. Q fever pneumonia: Apperance on chest radiographs

(2) Radiology 2000; Voloudaki AE, et al. Q fever pneumonia: CT findings. 215: 880-883

(3) J Nucl Med 2018; Kouijzer IJE, et al. The value of 18F-FDG PET/CT in diagnosis and during follow-up in 273 patients with chronic Q fever. 59: 127-133

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